Learn Cardiovascular system basics | MPO training 3

Learn Cardiovascular system basics with this simple and clear guide for Medical Promotion Officer (MPO) aspirants. This article explains how the heart and blood vessels work together.

learn-cardiovascular-system-basics
Diagram: Cardiovascular system diagram
It uses real-world examples and avoids medical jargon. Even if you’re new, you’ll understand quickly. Build confidence and grow your career step by step.

Table of content: Learn Cardiovascular system basics

What you will get in this blog post-

Learn Cardiovascular system basics

To learn cardiovascular system basics, start with how the heart pumps blood throughout your body. Understand the role of arteries, veins, and capillaries in blood circulation. This basic knowledge is essential for every Medical Promotion Officer (MPO). It helps you explain drug actions to doctors clearly. Begin with the simple structure and grow from there.


Here you can learn - Contents:
  • Description of the Cardiovascular System.
  • Physiology of the Cardiovascular System.
  • Monitoring and Diagnostic Techniques of the Cardiovascular System.

Cardiovascular System 

Cardiovascular system is a transport system that transports important substances 
around the body.

Components of the cardiovascular system are: 
  • Heart
  • Blood
  • Blood vessels

Blood and its composition

Blood is a suspension of cells in plasma.
  • Blood = Cell + Plasma.
Composition of Blood-
Blood-and-its-composition
Diagram: Blood vessel diagram

A. Cellular substance (cell):

  • Erythrocytes or RBC (Red Blood Corpuscles)
  • Leukocytes or WBC (White Blood Corpuscles)
  • Platelets or Thrombocytes

B. Liquid substance (Plasma):

  • Inorganic substance.
  • Organic substance (Proteins, Non protein nitrogenous substances, Fats, Carbohydrates and other).
Liquid-substance-Plasma

Plasma, plasma proteins and Serum

Plasma is the liquid part of blood, which is a solution of protein and salts.
  • Plasma = Serum + Coagulation proteins and factors.
Plasma

Plasma Proteins:

  • Albumin
  • Globulin
  • Fibrinogen

Serum

Serum is the fluid or the watery portion that remains after blood coagulation.
  • Serum = Plasma - coagulation proteins and factors.
Serum

Blood cells

Erythrocytes/RBC:

Erythrocytes-RBC
These are nucleus less cells containing hemoglobin and carry oxygen from the lung to all the tissues where it is exchanged for carbon dioxide.

Haemoglobin

It is the red pigment of the blood present in the RBC. Haemoglobin binds with oxygen and is converted to oxyhaemoglobin in the lung.

It is composed of two parts:
  • Haemoglobin = Haem (red pigment) + Globin (protein).

Leukocytes/WBC:

Leukocytes are defensive substances of the body, which defend against microorganisms that enter the body from the environment.
Leukocytes-WB
There are two types of WBC:

1) Granular:
  • Neutrophil
  • Basophil 
  • Eosinophil
2) Agranular:
  • Lymphocyte 
  • Monocyte

Thrombocytes/Platelet:

Platelets are substances that form plugs with coagulation proteins in the plasma to stop leaking from the blood vessels.
Thrombocytes-Platelet
Diagram: thrombocytes platelets diagram

General Properties of Blood

Blood volume is an average of 56 litres.
Blood pH value is 7.367.45.
Blood temperature is average 36-38 °C.
Viscosity of blood is 4.5 times more than that of water.

Functions of the Blood:

  • Transport function.
  • Regulation function.
  • Defensive function.
Functions-of-the-Blood

Blood vessels: Types 

The blood vessels are hollow tubes that carry the blood to and from the tissues.

There are three types of blood vessels:
  • Artery
  • Vein
  • Capillary
types-of-blood-vessels
Diagram: types of blood vessels diagram
Artery: Carries oxygenated blood from heart to all over the body.
Vein: Carries deoxygenated blood from all over the body to heart.
Capillary: Capillary are fine vessels that link or or junction the small arterioles and arterioles and smallest venules.

There are three layers in the blood vessels:

Tunica Intima: A thin layer of flat epithelial cells. The innermost layer of blood vessels.
Tunica Media: The middle layer composed of smooth muscle fibers and elastic fibers.
Tunica Adventitia: 👇
Tunica-Adventitia
Diagram: Tunica Adventitia diagram

Blood Circulation

Circulation is a process of blood flow through a closed system of vessels.
  • Systemic Circulation
  • Pulmonary Circulation
  • Coronary Circulation
  • Hepatic portal Circulation
Blood-Circulation
Diagram: Blood Circulation diagram

Importance of circulation:

  • To supply oxygen, nutrition, vitamins to the tissues.
  • To carry different metabolic waste products and carbon dioxide from tissue.
  • To prevent intravascular coagulation of blood.
  • To maintain an environment for cellular function.

Factors of maintaining Circulation:

  • Pumping action of heart.
  • Elastic recoil of arteries.
  • Pressure gradient.
  • Respiration.
  • Muscular exercise.

Blood Pressure

Blood Pressure is the pressure lateral exerted by the flowing blood on the wall of blood vessels.

Systolic Pressure: The pressure exerted by the blood on the blood vessels during contraction of the heart. It is 120 Hg for a normal person.
Blood-Pressure
Diagram: blood pressure diagram
Diastolic Pressure: The pressure exerted by the blood on the blood vessels during relaxation of the heart. It is 80 Hg for a normal person.

Blood Pressure for Adult

Blood Pressure for Adult
Category Systolic (mm Hg) Diastolic (mm Hg)
Normal <130 <85
High Normal 130-139 85-89
Blood Pressure for Adult
Hypertension Systolic (mm Hg) Diastolic (mm Hg)
Mild 140-159 90-99
Moderate 160-179 100-109 
Severe 180-209 110-119
Very Severe  210 or more 120 or more

Heart

Heart is the central blood-pumping organ of the body. It receives and pumps blood from and to all over the body. It is a hollow muscular organ.

A. Heart Chambers:

The Heart has four chambers:
The-Heart-has-four-chambers
Diagrame: Heart four chambers
* Receiving Chamber
  • Right atrium
  • Left atrium 
* Distributing Chamber
  • Right ventricle 
  • Left ventricle
Heart-Chambers
Diagrame: Heart chambers diagram

B. Heart Muscles:

The Pericardium: Outermost layer surrounding the heart.
The Myocardium: Middle muscular layer of the heart.
The Endocardium: The Innermost layer of the heart.
Heart-Muscles
Diagram: Heart Muscles diagram

C. Valves of Heart

Valve is a membranous structure that temporarily closes in order to permit flow of fluid in one direction.
Valves-of-Heart
Diagram: Valves of Heart diagram
There are four types of valves in the heart: 
  • Tricuspid or right atrio-ventricular valve.
  • Mitral valve or Left atrio-ventricular valve.
  • Pulmonary valve.
  • Aortic valve.

D. Heart Conduction System

Special tissues responsible for initiation and propagation of cardiac impulses.
Heart-Conduction-System
Diagram: Heart Conduction System diagram
These are: 
  • Sinoatrial node.
  • The Internodal pathway.
  • AtrioVentricular node.
  • The AtrioVentricular bundle/Bundle of His.
  • The left and right bundles of AV brunch.
  • The Purkinje fibers.

E. Heart Contraction nerve influences

There are two sets of nerves that influence the rate of contraction of the heart:
  • The Vagus nerve which slows the rate and lessens the strength of the beat.
  • The Sympathetic nerves which quickens and increase the strength of the beat.
Heart-Contraction-nerve-influences
Diagram: Heart Contraction nerve influences diagram

Effects on Heart

A. Effects on Heart: Potassium-

Excess potassium in the extracellular fluid causes-
  • The heart becomes extremely dilated.
  • Flaccid and slower heart rate.

B. Effects on Heart: Calcium

Excess calcium ion causes-
  • Increased Contraction of heart and blood vessels.

C. Effects on Heart : Sodium

Excess Sodium ion causes-
  • Depression of cardiac function.
  • Dilate and flaccid the heart.

D. Effects on Heart: Adrenaline 

Adrenaline increase the rate and force of contraction as it-
  • Stimulates S A Node.
  • Increases conductivity, contractility and automaticity.

Important Definitions

Heart Rate: The number of heart beats per minute is called heart rate.

Normal Heart rate-
  • Adult: 60-90/minute
  • Average: 72/minute
Cardiac Output: The amount of blood the heart pumps through the circulatory system in a minute.

Usually, an adult heart pumps about 5 liters of blood per minute at rest. But when you run or exercise, your heart may pump 3-4 times that much to make sure your body gets enough oxygen and fuel.


Tachycardia: The term tachycardia means a faster heart rate than the normal.
Usually above 100 beats/minute) is called tachycardia.

Bradycardia: The term bradycardia means slower heart rate than the normal physiological limit.
Usually below 60 beats/minutes is called bradycardia.

Hypertension 

Hypertension is a clinical condition in which the patient has a higher blood pressure than that judged to the normal.
Hypertension
Diagram: Hypertension diagram
Etiology:
  • Actual cause of hypertension is known.
Risk Factor: 
  • Generic 
  • Smoking
  • High lipid content
  • Overweight

Hypertension Types

Two types:

Essential or Primary Hypertension: Hypertension for which no cause is known is called primary or essential or idiopathic hypertension.
Hypertension-Types
Diagram: Types of Hypertension diagram
Secondary Hypertension: Hypertension for which the cause is known is called secondary hypertension.

Common Diseases

Anemia: Anemia is a reduction of hemoglobin concentration per unit of peripheral blood. As a result, Oxygen carrying capacity of blood is decreased.


Aplastic Anemia: Anemia which is due bone marrow depletion, is called Aplastic anemia.
Anemia
Leukemia: It is a disease due to abnormal increase in WBC.
Normal-leukemia
Endocarditis: Inflammation of Endocardium is called Endocarditis

Atherosclerosis: Atherosclerosis is a disease in which the inside of an artery narrows due to the buildup of plaque.
Atherosclerosis
Ischemic Heart Disease: Coronary artery disease (CAD), also known as Coronary heart disease (CHD), ischemic heart disease (IHD) or simply heart disease, involves the reduction of blood flow to the heart muscle due to build-up of plaque (atherosclerosis) in the arteries of the heart. It is the most common of the cardiovascular diseases.
Ischemic-Heart-Disease
Myocardial Infarction: A heart attack occurs when one of the heart's coronary arteries is blocked suddenly or has extremely slow blood flow. A heart attack also is called a myocardial infarction.
Myocardial-Infarction
Angina pectoris: Angina pectoris is the medical term for chest pain or discomfort due to coronary heart disease.
Angina-pectoris
Arrhythmia: Arrhythmia, also known as cardiac arrhythmia or heart arrhythmia, is a group of conditions in which the heartbeat is irregular, too fast, or too slow.

FAQs

Q. What is the full form of RBC?
A. The full form of RBC is Red Blood Corpuscles.

Q. What is the full form of WBC?
A. The full form of WBC is White Blood Corpuscles.

Q. What is another name for Platelets?
A. Another name for Platelets is Thrombocytes.

Conclusion

In conclusion, when you learn cardiovascular system basics, you take your first step toward being a smart and confident Medical Promotion Officer (MPO). This topic builds your understanding of how the human body works. It improves your communication with doctors. Simple knowledge leads to strong trust. So keep learning and move ahead with purpose.
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